Human Chorionic Gonadotropin: An Old Hormone with New Potentials
نویسندگان
چکیده
منابع مشابه
P-234: Expression of Human Chorionic Gonadotropin (hCG) Hormone Using Chinese Hamster Ovary Cells
Background: Human chorionic gonadotropin (hCG) is a member of glycoprotein hormones family consist of two different non-covalently heterodimeric chains: alpha and beta subunits with 92 and 145 amino acids respectively. This hormone plays an important role in human reproduction and physiology especially for maintenance of the corpus luteum during the first months of pregnancy Materials and Metho...
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A highly sensitive electrochemicalimmunosensor was developed to detect hCG based on immobilization ofhCG-antibody (anti-hCG) onto robust nanocomposite containing Gr, Chit,1-methyl-3-octyl imidazolium tetra fluoro borate ionic liquid (IL)(Gr-IL-Chit). AuNPs were used to immobilize hCG antibody on the modifiedelectrode. The amine groups of the antibody are cova...
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Luteinizing hormone (LH) and human chorionic gonadotropin (hCG) are widely recognized for their roles in ovulation and the support of early pregnancy. Aside from the timing of expression, however, the differences between LH and hCG have largely been overlooked in the clinical realm because of their similar molecular structures and shared receptor. With technologic advancements, including the de...
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LH/hCG receptors were disrupted by gene targeting in embryonic stem cells. The disruption resulted in infertility in both sexes. The gonads contained no receptor mRNA or receptor protein. Serum LH levels were greatly elevated, and FSH levels were moderately elevated in both sexes; estradiol and progesterone levels decreased but were not totally suppressed in females; testosterone levels were dr...
متن کاملLuteinizing hormone and human chorionic gonadotropin: distinguishing unique physiologic roles
Luteinizing hormone (LH) and human chorionic gonadotropin (hCG) are integral components of the hypothalamic-pituitary-gonadal axis, which controls sexual maturation and functionality. In the absence of signaling through their shared receptor, fetal sexual differentiation and post-natal development cannot proceed normally. Although they share a high degree of homology, the physiologic roles of t...
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ژورنال
عنوان ژورنال: Reproductive Immunology: Open Access
سال: 2016
ISSN: 2476-1974
DOI: 10.21767/2476-1974.100016